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'Conviction list' stocks with big upside Investors still looking for quality names with more upside may want to consider names in Goldman's conviction lists — directors' cut. CNBC Pro scoured Goldman's May conviction lists for stocks with further upside of 50% or more, based on the bank's price targets. Goldman gave it a price target of $35, implying 107% upside. Goldman gave it a price target of 37 euros ($40), implying 64% upside. The bank gave the stock a price target of 380,000 Korean won ($277), or potential upside of 94%.
Persons: Stocks, Goldman Sachs, Peter Oppenheimer, Goldman, Neste, — CNBC's Michael Bloom Organizations: Dow Jones, U.S . Federal, Fed, CNBC, Europe's, Energy, Korean Locations: 1Q24, United States, Europe, Asia, Korean
CNN —Ask Jane Seymour about her longevity as an actress and she can point to several things, including her willingness to take on a variety of roles. The show, which Seymour also executive produces, has humor as well as mystery and it’s a natural fit for the “Dr. There’s no too small a role.”And there’s no role too emotional for Seymour either. These days Seymour has found love with her boyfriend John Zambetti, who is a doctor and a musician. Now he says ‘Can we watch Dr. Quinn?’”Season 3 of “Harry Wild” premieres Monday on AcornTV.
Persons: Jane Seymour, “ I’m, Harry Wild ”, Harriet “ Harry ” Wild, Fergus, Rohan Nedd, Seymour, Quinn, , , Harry, Glen Campbell, Alzheimer’s, “ Glen Campbell, James Keach, John Zambetti, She, Dr, James Bond, , “ He’d, Quinn ’ Organizations: CNN, Medicine Locations: Covid, AcornTV
Eating certain types of UPFs carries a higher risk of early death than others, a new study found. AdvertisementPeople who eat a lot of ultra-processed foods are more likely to die early than those who don't, according to a study. Chan School of Public Health, told CNN that the association between UPFs and early death was "moderate" and not equally strong among all UPFs. Notably, a recent study linked UPFs to 32 health problems, including cancer, cardiovascular disease, and depression. To address these concerns, the researchers placed UPFs into nine groups to assess if some foods had a greater impact than others.
Persons: , Mingyang, Harvard T.H, UPF, Gunter Kuhnle Organizations: Service, Harvard, of Public Health, CNN, University of Reading Locations: Chan, UPFs
CNN —Has your doctor quizzed you about your level of physical activity? If so, you can thank Exercise is Medicine, a global health initiative managed by the American College of Sports Medicine. Created in 2007, the initiative encourages health care providers to assess patients’ physical activity during visits, plus include regular exercise when designing care plans. Health care providers can impact patient health by routinely assessing physical activity at every interaction. EIM now includes Exercise is Medicine on Campus, for example, a program that helps colleges and universities promote and assess physical activity among students, faculty and staff.
Persons: CNN —, Jacob Wackerhausen, Elizabeth Joy, EIM, Joy, it’s, ” Joy, , Amy Campbell, GVSU, Campbell, ” Campbell, There’s, you’ve, “ Rather, Gerren Liles, “ It’s, , Melanie Radzicki McManus Organizations: CNN’s, CNN, American College of Sports Medicine, American, of Lifestyle Medicine, Intermountain, Lore Health, Health, Grand Valley State University, EIM, CARE, Cancer, New Locations: Salt Lake City, Grand, Grand Rapids , Michigan, they’ll, EIM, New York, New York City, Liles
Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.
Persons: APOE4, , Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, , ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin
People have wanted to reconnect with deceased loved ones for centuries, whether they’ve visited mediums and spiritualists or leaned on services that preserve their memory. In September 2023, it introduced ChatGPT voice, where users can ask the chatbot prompts without typing. HereAfter AI, founded in 2019, allows users to create avatars of deceased loved ones. “Remembering is very important; it reflects the human condition and importance of deceased loved ones.”But she noted the relationship we have with our closest loved ones is built on authenticity. Creating an AI version of that person could for many “feel like a violation of that.”Bill Abney said he feels uneasy about communicating with his late fiancée through AI platforms.
Persons: Ana Schultz, Kyle, , Schultz, , Schutz, they’ve, ” Ana Schultz, ElevenLabs, Joe Biden, Biden, ChatGPT, OpenAI, Danielle Jacobson, she’s, Phil, Cole, ” Jacobson, “ Cole, Replika, Rohit Prasad, Val Kilmer, It’s, Mary, Frances O’Connor, , ’ ”, Bill Abney, Kari, ” Abney, “ I’m, Jodi Spiegel, Sims Organizations: CNN, Davidson College, Tech, Alexa, MARS, Amazon, University of Arizona Locations: Rock Falls , Illinois, Alabama, Johannesburg, South Africa, , San Francisco, Newfoundland, Canada
Scientists are proposing a new way of understanding the genetics of Alzheimer’s that would mean that up to a fifth of patients would be considered to have a genetically caused form of the disease. Currently, the vast majority of Alzheimer’s cases do not have a clearly identified cause. The new designation, proposed in a study published Monday, could broaden the scope of efforts to develop treatments, including gene therapy, and affect the design of clinical trials. It could also mean that hundreds of thousands of people in the United States alone could, if they chose, receive a diagnosis of Alzheimer’s before developing any symptoms of cognitive decline, although there currently are no treatments for people at that stage. The new classification would make this type of Alzheimer’s one of the most common genetic disorders in the world, medical experts said.
Locations: United States
Olive oil may lower risk of dementia-related death
  + stars: | 2024-05-06 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +5 min
CNN —A daily spoonful of olive oil could lower your risk of dying from dementia, according to a new study by Harvard scientists. Olive oil can be a healthy, tasty addition to foods such as sandwiches and salads. Replacing 5 grams — around 1.2 teaspoons — of margarine or mayonnaise consumed daily with olive oil was associated with an 8% to 14% lower risk of death from dementia. “It is also possible that olive oil has an indirect effect on brain health by benefiting cardiovascular health,” she added. Besides cooking with olive oil, you can also use it to make salad dressings or vinaigrettes, mayonnaise, pesto or bread dip.
Persons: Anne, Julie Tessier, Harvard University’s T.H, , Duane Mellor, ” Mellor, Tessier, , David Curtis, Mellor, Curtis, Olive, it’s Organizations: CNN, Harvard, JAMA, American Society, Harvard University’s, of Public Health, Nurses, Health, Aston Medical School, Aston University, University College London Locations: Chan, North America, United Kingdom
Peter Oosterhuis, a British golfer who won 20 tournaments around the world, played in the Ryder Cup six times and later distinguished himself as a commentator for CBS and Golf Channel, died on Thursday in Charlotte, N.C. His wife, Ruth Ann (DuClos) Oosterhuis, said that his death, at a memory care facility, was caused by complications of Alzheimer’s disease. That year, Oosterhuis (pronounced OH-ster-house) spoke to Golf Digest about his life and career. One detailed memory he still had: “In the 1973 Ryder Cup, I played Lee Trevino in one of my singles matches. Lee told his teammates, ‘If I don’t beat Oosterhuis, I’ll come in here and kiss your butts.’ Lee didn’t beat me.”
Persons: Peter Oosterhuis, Ruth Ann, Oosterhuis, , , Lee Trevino, Lee, I’ll, ’ Lee didn’t Organizations: Ryder, CBS, Golf, Digest Locations: British, Charlotte, N.C
Robert B. Oxnam, an eminent China scholar who learned through psychotherapy that his years of erratic behavior could be explained by the torment of having multiple personalities, died on April 18 at his home in Greenport, N.Y., on the North Fork of Long Island. In the 1ate 1980s, Dr. Oxnam was president of the Asia Society, a television commentator and an accomplished sailor. In his 2005 book, “A Fractured Mind: My Life With Multiple Personality Disorder,” Dr. Oxnam recalled the session when Tommy first spoke to Dr. Smith. All that Dr. Oxnam could remember from the 50-minute session, he wrote, was telling the psychiatrist that he didn’t think the therapy was working for him. But Dr. Smith told him that he had been speaking to Tommy all that time.
Persons: Robert B, Vishakha Desai, Oxnam, Jeffery Smith, Bobby, Tommy, Smith Organizations: Asia Society Locations: China, Greenport, Long
Scientists identify ‘degrees of Kevin Bacon’ gene
  + stars: | 2024-05-02 | by ( Katie Hunt | ) edition.cnn.com   time to read: +6 min
Even humble fruit flies organize themselves into regularly spaced clusters, researchers have found. Within those social networks, certain individuals will often stand out as “gatekeepers,” playing an important role for cohesion and communication within that group. New research published Tuesday in the journal Nature Communications has identified a gene responsible for regulating the structure of social networks in fruit flies. The study opened up new opportunities for exploring the molecular evolution of social networks and collective behavior in other animals. FLPA/ShutterstockThe gene behind fruit fly social networksThe researchers investigated a number of gene candidates in fruit flies, a common lab organism used in the study of genetics.
Persons: , Kevin Bacon, Bacon, Joel Levine, Rebecca Rooke, ” Levine, Levine, , ” Allen J, Moore, wasn’t, ” Moore Organizations: CNN, Nature Communications, University of Toronto, University of Georgia’s Locations: Philadelphia, University of Toronto Mississauga
“If we work with our physiology knowing that women are women and men are men, knowing that women are not small men, then imagine the (health) outcomes,” she said at a 2019 TED talk. Women of all ages should focus on strength training to help reduce risk of dementia, said exercise physiologist and nutrition scientist Dr. Stacy Sims (not shown). Dr. Stacy Sims said women should prioritize eating more protein to support building muscle, especially as bodies age. But if we have that lean mass from strength training, it really helps calm down that rate of change. Drinking something cold right after exercise helps bring that blood back centrally, reduces metabolites and starts the reparation process.
Persons: Joe Biden, , Stacy Sims, , MoMo, Sims, Darwin, that’s, Alzheimer’s, haven’t, It’s, , Melanie Radzicki McManus Organizations: CNN’s, CNN, TED, National Institutes of Health, Women’s, US National Institutes of Health Locations: Mount Maunganui , New Zealand
Eli Lilly 's raised guidance stole the show Tuesday, offsetting mixed first-quarter results and propelling shares higher by nearly 6%. Eli Lilly Why we own it: Eli Lilly's best-in-class drugs should enable growth above the industry average for many years to come. At their highs of the morning, shares of Eli Lilly traded above their all-time closing high of $792.28 set on March 4. In general, the more-bullish financial outlook helps make Eli Lilly's high price-to-earnings ratio coming into earnings more tolerable for investors. An injection pen of Zepbound, Eli Lilly’s weight loss drug, is displayed in New York City, U.S., December 11, 2023.
Persons: Eli Lilly, Eli Lilly's, Lilly, Jim Cramer, Lilly's, Jim, Anat Ashkenazi, Zepbound, It's, Ashkenazi, Dave Ricks, donanemab, Jim Cramer's, Eli Lilly’s, Brendan McDermid Organizations: Revenue, LSEG, Novo Nordisk, Biogen, Merck, Pfizer, U.S, Drug Administration, Nexus Pharmaceuticals, CNBC, FDA Locations: Eisai, Zepbound, Trulicity, Wisconsin, New York City, U.S
Sandra TorresTorres has a rare disorder called Laron syndrome that is caused by a genetic mutation. “This is how powerful this mutation seems to be.”What is Laron syndrome? Laron syndrome is a recessive gene, so only those who receive a copy from each parent will be affected. The condition leads to extreme obesity, a trigger for diabetes, heart disease, cancer and other diseases. While technically overweight at 100 pounds (45.4 kilograms), she was in good health, with no signs of diabetes or heart disease.
Persons: Paola Castro Torres, ” Torres, Torres, , ” Nathaly Paola Castro Torres, Sandra Torres Torres, , Valter Longo, Longo, Laron, Jaime Guevara, Aguirre, Guevara, ” Longo, ” Guevara, Andrew Freeman, Freeman, ” Hope, it’s Organizations: CNN, gerontology, University of Southern, of Endocrinology, Laron, Jewish Health Locations: Los Angeles, Quito, Ecuador, University of Southern California, Israel, Yemen, East, United States, Croatia, Ireland, Denver
However, many people didn't understand that it wasn't an Alzheimer's diagnosis, Hemsworth told Vanity Fair. Dementia is an umbrella term to describe serious memory and thinking problems, while Alzheimer's is a specific disease that can progress into dementia. Hemsworth previously told Men's Health that he's started doing more cardio, taking more alone time, being more mindful, and prioritizing sleep. "I think for the first time in my career, I've started thinking, 'Shit, how many years do I have left that I can do this?'" "I know my dad is going through a transition of acceptance around 'I'm not this big, strong man with all the answers who everybody looks to for guidance now,'" Hemsworth told the publication.
Persons: , Chris Hemsworth wasn't, Hemsworth, Men's, he's, I've, Hemsworth's, Craig Organizations: Service, Geographic, Business, Hemsworth, Men's Health Locations: Hemsworth
GE Healthcare shares sank Tuesday after the company's first-quarter sales and profits fell slightly short of the Wall Street consensus. GE Healthcare Why we own it : GE Healthcare is the global leader in medical imaging, diagnostics, and digital solutions in health care. That's what we have to say about this GE Healthcare quarter. This contributed to some of the softness in the first quarter quarter. The GE Healthcare scanner is called the Revolution CT. Martin Schutt | picture alliance | Getty Images
Persons: didn't, GE Healthcare's, , it's, Peter Arduini, Jim Cramer's, Jim Cramer, Jim, Martin Schutt Organizations: GE Healthcare, LSEG, General Electric, Philips, Siemens, GE Healthcare YTD, GE, Management, Alzheimer's, CNBC, Getty Locations: China, Covid, Jena , Germany
Tirzepatide is the active ingredient in both Eli Lilly's diabetes treatment Mounjaro and its anti-obesity drug Zepbound. Based on that calculation, earnings will be lower by about 13 cents per share, he said, in research published last Tuesday. "Strong demand for Mounjaro & Zepbound can easily pull through in 2H24 and make up for any 1H24 shortfalls." For the week ended April 19, combined prescriptions of Mounjaro and Zepbound rose 63% year over year, according to IQVIA. Wells Fargo Mohit Bansal said he expects investors to look past any Trulicity shortfalls as the focus is firmily on Zepbound and Mounjaro for Lilly's future growth.
Persons: Eli Lilly, Eli, James Shin, Lilly, Shin, David Risinger, Zepbound, Wells, Bansal, Jo Walton, Walton, Lilly's, Tirzepatide, Deutsche Bank's Shin, — CNBC's Michael Bloom Organizations: Drug Administration, Deutsche Bank, IMS, UBS, Research, Deutsche, FDA Locations: 2H24, U.S
It's a week jam-packed with notable events, including earnings from Apple , Amazon and Eli Lilly . He also said to pay attention to Wednesday's Federal Reserve meeting and Friday's employment figures from the Department of Labor. "We have to run such a ridiculous gauntlet next week that I have no idea how it'll play out," he said. Wednesday also brings reports from Wingstop , Carvana and Marriott . Apple will report on Thursday, and Cramer noted there's been a lot of negative sentiment from investors surrounding the company.
Persons: CNBC's Jim Cramer, Eli Lilly, Jensen Huang, Cramer, it's, he'll, Seagen, there's Organizations: Apple, Federal Reserve, Department of Labor, Nvidia, Food and Drug Administration, Starbucks, CVS, Pfizer, Amazon, Walgreens, Marriott, Vision Locations: It's, China, Wingstop, Carvana
Hilton Worldwide Holdings — The hotel stock climbed 4% on the back of strong first-quarter adjusted earnings and raised full-year guidance. Mattel saw $810 million in revenue during the quarterly period, which was less than the consensus estimate of $832 million. Adjusted earnings per share came in at 61 cents, beating analysts' expectations of 27 cents per share, according to LSEG. Revenue of $757 million was greater than the $739 million analysts anticipated. Sales of Biogen's Alzheimer's drug Leqembi came in at about $19 million for the quarter, surpassing the $11 million analysts had anticipated, per FactSet.
Persons: LSEG, Elon Musk, Tesla, Musk's, Hilton, Mattel, Enphase, Biogen, LSEG ., Leqembi, , Jesse Pound, Alex Harring, Michelle Fox, Lisa Han Organizations: Boeing, . Old Dominion, Hilton Worldwide Holdings, Texas, Mattel, LSEG, Hasbro, Enphase Energy, Dynamics —, Dynamics, Seagate Technology, Seagate Locations: FactSet, LSEG
Biogen on Wednesday reported first-quarter profit that topped estimates as the company's cost-cutting efforts took hold and sales of its closely watched Alzheimer's drug, Leqembi, came in higher than expected. Biogen and Eisai 's Leqembi became the first drug found to slow the progression of Alzheimer's disease to win approval in the U.S. in July. Leqembi brought in about $19 million in sales for the quarter, up from the $10 million the drug generated last year. In February, Biogen CEO Chris Viehbacher told reporters that there were around 2,000 patients currently on Leqembi. Adjusting for one-time items, the company reported earnings of $3.67 per share.
Persons: Biogen, Leqembi, FactSet, Chris Viehbacher, LSEG Organizations: LSEG Locations: U.S
Last year was called the year of Ozempic, though it was also a year of Ozempic backlash and Ozempic shortages, which could persist for years. Even so, we appear very far from a peak for GLP-1 drugs, like Ozempic and Wegovy, which are powered by a molecule called semaglutide, and Mounjaro, which uses its cousin tirzepatide. It seems possible to imagine a future in which almost everyone is taking some variety of GLP-1 drug, and with a pretty good reason to do so. Patients on Ozempic and Wegovy can lose 15 to 20 percent or more of their weight in a little over a year, and if they stay on the drugs, the weight tends to stay off. Semaglutide has been shown to eliminate or reduce the need for insulin among those with recent-onset Type 1 diabetes.
Persons: tirzepatide, Wegovy, we’ve, Semaglutide Locations: Alzheimer’s
Airbnb – The vacation property rental platform added nearly 2% following an upgrade by Mizuho to buy from neutral. Visa — Shares of the payment company rose more than 2% after stronger than expected results for the second fiscal quarter. Texas Instruments posted $1.20 per share on $3.66 billion in revenue, beating analysts' projections of $1.07 and $3.61 billion, respectively, per LSEG. Mattel saw $810 million in revenue during the quarterly period, which was less than the consensus estimate of $832 million. Enphase said to expect second-quarter revenue between $290 million and $330 million, under the consensus forecast of $349 million.
Persons: Mizuho, Elon Musk, Tesla, LSEG, , Enphase, Alex Harring, Samantha Subin, Jesse Pound, Brian Evans, Yun Li, Sarah Min, Michelle Fox Theobald Organizations: Boeing —, Boeing, Mizuho, Summer Olympics, Visa —, Visa, Revenue, Texas, Sea, Capital, Mattel, LSEG, Enphase Energy
GLP-1 drugs were originally developed to treat type 2 diabetes. Drugmakers are discovering the injections may also aid weight loss, heart issues, and sleep apnea. AdvertisementAnother new indication for injectable GLP-1 drugs: better sleep. On Wednesday, drugmaker Eli Lilly announced positive results from a large, phase-3 clinical trial, testing Zepbound (the drug name for tirzepatide) as a treatment for sleep apnea. Related storyAlready, GLP-1 drugs have been indicated for the treatment of:ObesityHeart diseaseAdvertisementIn clinical trials, GLP-1 drugs have also shown some promise for treating other conditions, including:Non-alcoholic fatty liver diseaseAddictionDepressionParkinson's and Alzheimer'sCancerThese breakthroughs may be tied to the gut-brain connectionScientists think that the main reason GLP-1 drugs work well is because of their effect on our body's gut-brain connection.
Persons: , drugmaker Eli Lilly, Eli Lilly, KATERYNA, Daniel Drucker, GLP, Eric Topol Organizations: Service, Food and Drug Administration, American Diabetes Association, University of Toronto
Having a routine job with little mental stimulation during your 30s, 40s, 50s and 60s was linked to a 66% higher risk of mild cognitive impairment and a 37% greater risk of dementia after the age of 70, according to the study, when compared with having a job with high cognitive and interpersonal demands. Attending college, for example, reduced the impact of a repetitive job by about 60% but didn’t fully negate the risk. Routine jobs that were not classified as “cognitively protective” often involved repetitive manual and mental tasks, such as is typical of factory work and bookkeeping. “Most people in routine jobs in our sample included housekeepers, custodians, construction workers and mail carriers,” Edwin said. More cognitively demanding jobs were not based on routine tasks, even though repetition was required at times.
Persons: , Dr, Trine Edwin, Edwin said, Richard Isaacson, Isaacson, ” Edwin, Edwin, It’s, ” Isaacson Organizations: CNN, Oslo University Hospital, American Academy of Neurology, Locations: Norway, Florida
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